1. Digital Repository at Indian Institute of Science Education and Research Pune
  2. PUBLICATIONS & PATENTS
  3. JOURNAL ARTICLES
Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/10080
Full metadata record
DC FieldValueLanguage
dc.contributor.authorRAIGAWALI, RAKESHen_US
dc.contributor.authorANAND, SAURABHen_US
dc.contributor.authorCHANDRA, ANKITAen_US
dc.contributor.authorMAHIDA, VIRENDRASINHen_US
dc.contributor.authorBHOGE, PREETI RAVINDRAen_US
dc.contributor.authorABRAHAM, JANCY NIXONen_US
dc.contributor.authorKIKKERI, RAGHAVENDRAen_US
dc.date.accessioned2025-05-22T05:11:40Z
dc.date.available2025-05-22T05:11:40Z
dc.date.issued2025-05en_US
dc.identifier.citationChemical Communicationsen_US
dc.identifier.issn1359-7345en_US
dc.identifier.issn1364-548Xen_US
dc.identifier.urihttps://doi.org/10.1039/D5CC00527Ben_US
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/10080
dc.description.abstractHerein, we report the synthesis of heparan sulfate (HS) proteoglycan mimetics bearing iduronic acid (IdoA) and sulfated L-idose (Ido) hexasaccharides to assess how these isostructural sugars with similar charge density influence neoproteoglycan display on the cell membrane. PG@I2, carrying sulfated L-idose, showed rapid internalization in both cancerous and normal cells, whereas PG@I1, containing native IdoA expressed on the cell membrane and slowly internalized, underscoring the role of IdoA in HSPG cell surface engineering.en_US
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.subjectHeparan-Sulfateen_US
dc.subjectAntithrombinen_US
dc.subjectActivationen_US
dc.subjectBindingen_US
dc.subject2025-MAY-WEEK3en_US
dc.subjectTOC-MAY-2025en_US
dc.subject2025en_US
dc.titleComparative analysis of sulfated l-idose and l-iduronic acid in neoproteoglycan cell surface engineeringen_US
dc.typeArticleen_US
dc.contributor.departmentDept. of Biologyen_US
dc.identifier.sourcetitleChemical Communicationsen_US
dc.publication.originofpublisherForeignen_US
Appears in Collections:JOURNAL ARTICLES

Files in This Item:
There are no files associated with this item.
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.