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http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1435| Title: | DNA Nanocarriers: Programmed to Deliver |
| Authors: | MADHANAGOPAL, BHARATH RAJ Zhang, Shunqing et al. Dept. of Biology |
| Keywords: | DNA nanotechnology Drug delivery DNA origami Nanocarriers DNA nanocages DNA nanostructures TOC-DEC-2018 2018 |
| Issue Date: | Dec-2018 |
| Publisher: | Elsevier B.V. |
| Citation: | Trends in Biochemical Sciences, 43(12) pp997-1013. |
| Abstract: | DNA can be used as a building block for creating nanoscale structures.DNA nanostructures are programmable, offering unique characteristics for use as drug delivery carriers.DNA nanocarriers can be targeted to specific cells; be triggered using chemical, molecular or environment cues to release drugs; and offer tunable cellular uptake profiles.DNA nanocarriers are used for a variety of cargos including small molecules, therapeutic oligonucleotides, antibodies, peptides, and photosensitizers.Nanocarriers can be functionalized to provide a -see-and-treat- strategy for the creation of theranostics. |
| URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1435 https://doi.org/10.1016/j.tibs.2018.09.010 |
| ISSN: | 0968-0004 1362-4326 |
| Appears in Collections: | JOURNAL ARTICLES |
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