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DC Field | Value | Language |
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dc.contributor.author | Nandurdikar, Rahul S. | en_US |
dc.contributor.author | Maciag, Anna E. | en_US |
dc.contributor.author | Hong, Sam Y. | en_US |
dc.contributor.author | CHAKRAPANI, HARINATH | en_US |
dc.contributor.author | Citro, Michael L. | en_US |
dc.contributor.author | Keefer, Larry K. | en_US |
dc.contributor.author | Saavedra, Joseph E. | en_US |
dc.date.accessioned | 2019-01-21T10:29:25Z | |
dc.date.available | 2019-01-21T10:29:25Z | |
dc.date.issued | 2009-12 | en_US |
dc.identifier.citation | Organic Letters, 12(1), 56-59. | en_US |
dc.identifier.issn | 1523-7060 | en_US |
dc.identifier.issn | 1523-7052 | en_US |
dc.identifier.uri | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1485 | - |
dc.identifier.uri | https://doi.org/10.1021/ol902481s | en_US |
dc.description.abstract | GlcNAc-PROLI/NO prodrugs that are activated by N-acetylglucosaminidase to release nitric oxide (NO) are described. A classical acid-amine coupling is used to bifunctionalize these PROLI/NO prodrugs, which on activation generate up to 4 mol of NO, a peptide residue, and an N-acetylglucosamine residue. Many of the prodrugs synthesized are efficient sources of intracellular NO. | en_US |
dc.language.iso | en | en_US |
dc.publisher | American Chemical Society | en_US |
dc.subject | PROLI/NO | en_US |
dc.subject | lysine methyl | en_US |
dc.subject | Glycosidase | en_US |
dc.subject | Peptide residue | en_US |
dc.subject | 2010 | en_US |
dc.title | Glycosylated PROLI/NO Derivatives as Nitric Oxide Prodrugs | en_US |
dc.type | Article | en_US |
dc.contributor.department | Dept. of Chemistry | en_US |
dc.identifier.sourcetitle | Organic Letters | en_US |
dc.publication.originofpublisher | Foreign | en_US |
Appears in Collections: | JOURNAL ARTICLES |
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