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Title: | Benzosultines as Sulfur Dioxide (SO2) Donors |
Authors: | MALWAL, SATISH R. GUDEM, MAHESH HAZRA, ANIRBAN CHAKRAPANI, HARINATH Dept. of Chemistry |
Keywords: | Benzosultines Sulfur Dioxide (SO2) Donors Fossil fuels Cycloreversion Benzosultines 2013 |
Issue Date: | Mar-2013 |
Publisher: | American Chemical Society |
Citation: | Organic Letters, 15(5), 1116-1119. |
Abstract: | In order to understand precise biological roles of sulfur dioxide (SO2), reliable SO2 donors, compounds that produce SO2 under physiological conditions, are necessary. The design and development of 1-phenyl-benzosultine as an efficient SO2 donor is reported. This compound undergoes cycloreversion to generate SO2 upon dissolution in aqueous buffer at 37 °C with a yield of 89% and a half-life of 39 min and shows SO2-like biological activity in a DNA cleavage assay. |
URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1586 https://doi.org/10.1021/ol400190f |
ISSN: | 1523-7060 1523-7052 |
Appears in Collections: | JOURNAL ARTICLES |
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