Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1586
Title: Benzosultines as Sulfur Dioxide (SO2) Donors
Authors: MALWAL, SATISH R.
GUDEM, MAHESH
HAZRA, ANIRBAN
CHAKRAPANI, HARINATH
Dept. of Chemistry
Keywords: Benzosultines
Sulfur Dioxide
(SO2) Donors
Fossil fuels
Cycloreversion
Benzosultines
2013
Issue Date: Mar-2013
Publisher: American Chemical Society
Citation: Organic Letters, 15(5), 1116-1119.
Abstract: In order to understand precise biological roles of sulfur dioxide (SO2), reliable SO2 donors, compounds that produce SO2 under physiological conditions, are necessary. The design and development of 1-phenyl-benzosultine as an efficient SO2 donor is reported. This compound undergoes cycloreversion to generate SO2 upon dissolution in aqueous buffer at 37 °C with a yield of 89% and a half-life of 39 min and shows SO2-like biological activity in a DNA cleavage assay.
URI: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1586
https://doi.org/10.1021/ol400190f
ISSN: 1523-7060
1523-7052
Appears in Collections:JOURNAL ARTICLES

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