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dc.contributor.authorKAYASTHA, ABHIJEET K.en_US
dc.contributor.authorHOTHA, SRINIVASen_US
dc.date.accessioned2019-02-14T05:00:10Z
dc.date.available2019-02-14T05:00:10Z
dc.date.issued2013-10en_US
dc.identifier.citationBeilstein Journal of Organic Chemistry, 9, 2147-2155.en_US
dc.identifier.issn1860-5397en_US
dc.identifier.issn1860-5397en_US
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1596-
dc.identifier.urihttps://doi.org/10.3762/bjoc.9.252en_US
dc.description.abstractThe synthesis of oligosaccharides is still a challenging task as there is no universal glycosyl donor for the synthesis of all oligosaccharides. The gold catalysis for glycosidation reactions, in which alkynylated glycosides are used, has emerged as one of the versatile options in this regard. A cleavage of the interglycosidic bond that was thought to be due to the higher reaction temperature and the acidic medium was observed during the synthesis of trisaccharides. In addition, a very little percentage of deprotection of benzyl protecting groups at the C-6 position was observed and no deprotection of benzyl ethers in aliphatic molecules was noticed. In order to overcome this fact, a collection of leaving groups that contain an alkynyl moiety were screened. It was found that 1-ethynylcyclohexanyl (Ech) glycosides are suitable for carrying out the glycosidation at 25 °C in the presence of 5 mol % each of AuCl3 and AgSbF6. Subsequently, Ech-glycosides were observed to be suitable for the synthesis of trisaccharides under gold catalysis conditions.en_US
dc.language.isoenen_US
dc.publisherBeilstein-Instituteen_US
dc.subjectGold-catalyzeden_US
dc.subjectTrisaccharidesen_US
dc.subjectArmed-disarmed strategyen_US
dc.subjectoligosaccharidesen_US
dc.subjectAlkynesen_US
dc.subject2013en_US
dc.titleGold-catalyzed glycosidation for the synthesis of trisaccharides by applying the armed–disarmed strategyen_US
dc.typeArticleen_US
dc.contributor.departmentDept. of Chemistryen_US
dc.identifier.sourcetitleBeilstein Journal of Organic Chemistryen_US
dc.publication.originofpublisherForeignen_US
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