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http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1921| Title: | Chemoselective N-deacetylation under mild conditions |
| Authors: | SULTANE, PRAKASH R. Trimbak B. Mete BHAT, RAMAKRISHNA G. Dept. of Chemistry |
| Keywords: | Chemoselective N-deacetylation Mild conditions Deprotection conditions Epimerization at the chiral amino centre 2013 |
| Issue Date: | Oct-2013 |
| Publisher: | Royal Society of Chemistry |
| Citation: | Organic and Biomolecular Chemistry, 12(2), 261-264. |
| Abstract: | A mild and efficient chemoselective N-deacetylation using the Schwartz reagent at room temperature in rapid time is described. The mild and neutral conditions enable orthogonal N-deacetylation in the presence of some of the common protecting groups (viz. Boc, Fmoc, Cbz, Ts). The deprotection conditions did not induce any epimerization at the chiral amino centre. |
| URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1921 https://doi.org/10.1039/C3OB41971A |
| ISSN: | 1477-0520 1477-0539 |
| Appears in Collections: | JOURNAL ARTICLES |
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