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Title: | A phenacrylate scaffold for tunable thiol activation and release |
Authors: | SANKAR, RATHINAM K. Kumbhare, Rohan S. DHARMARAJA, ALLIMUTHU T. CHAKRAPANI, HARINATH Dept. of Chemistry |
Keywords: | Phenacrylat Thiol activation Biochemistry Structural modifications Fluorescence microscopy 2014 |
Issue Date: | Oct-2014 |
Publisher: | Royal Society of Chemistry |
Citation: | Chemical Communications, 50(97), 15323-15326. |
Abstract: | A thiol-selective 2-methyl-3-phenacrylate scaffold with spatiotemporal control over delivery of a cargo is reported. The half-lives of decomposition could be tuned from 30 min to 1 day and the scaffold's utility in thiol-inducible fluorophore release in cell-free as well as within cells is demonstrated. |
URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1922 https://doi.org/10.1039/C4CC07343F |
ISSN: | 1359-7345 1364-548X |
Appears in Collections: | JOURNAL ARTICLES |
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