A fluorescent off–on NBD-probe for F− sensing: theoretical validation and experimental studies

Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2101

Title:	A fluorescent off–on NBD-probe for F− sensing: theoretical validation and experimental studies
Authors:	Roy, Arundhati Datar, Avdhoot KAND, DNYANESHWAR Saha, Tanmoy TALUKDAR, PINAKI Dept. of Chemistry
Keywords:	Experimental studies F? sensing Cell imaging Ammonium fluoride 2014
Issue Date:	Jan-2014
Publisher:	Royal Society of Chemistry
Citation:	Organic and Biomolecular Chemistry, 12(13), 2143-2149 .
Abstract:	The design, synthesis and fluoride sensing ability of a 7-nitro-2,1,3-benzoxadiazole (NBD) based chemodosimeter is reported. Theoretical calculations were used to design a more applicable off–on response, by choosing NBD as the accurate fluorophore. Reaction of the NBD-probe with 300 equivalents of tetrabutyl ammonium fluoride (TBAF) exhibited a response time of 80 minutes and the reaction was selective to F− and sensing of the ion was marked by a 110-fold enhancement of green fluorescence. The off–on fluorescence characteristics of the probe enabled its application in live-cell imaging of intracellular F− ions.
URI:	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2101 https://doi.org/10.1039/C3OB41886C
ISSN:	1477-0520 1477-0539
Appears in Collections:	JOURNAL ARTICLES

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