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Title: | A rationally designed peptidomimetic biosensor for sialic acid on cell surfaces |
Authors: | Chaudhary, Preeti Madhukar Murthy, Raghavendra Vasudeva Yadav, Rohan KIKKERI, RAGHAVENDRA Dept. of Chemistry |
Keywords: | Rationally designed Peptidomimetic Cell surfaces Biomacromolecules SNA stained HeLa 2015 |
Issue Date: | Apr-2015 |
Publisher: | Royal Society of Chemistry |
Citation: | Chemical Communications, 51(38), 8112-8115. |
Abstract: | We have developed peptidomimetic sialic acid (Sia) biosensors using boronic acid and arginine groups on the peptide backbone. The designed peptides were conjugated to fluorescent streptavidin via biotin enabling the optical labeling of cells. This approach provides unique opportunities to detect Sia composition on the cell surfaces and filopodia. |
URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2160 https://doi.org/10.1039/C5CC01662B |
ISSN: | 1359-7345 1364-548X |
Appears in Collections: | JOURNAL ARTICLES |
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