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http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2163| Title: | Assessing the effect of different shapes of glyco-gold nanoparticles on bacterial adhesion and infections |
| Authors: | Chaudhary, Preeti Madhukar Sangabathuni, Sivakoti Murthy, Raghavendra Vasudeva Paul, Ajay Thulasiram, Hirekodathakallu V. KIKKERI, RAGHAVENDRA Dept. of Chemistry |
| Keywords: | Glyco-gold nanoparticles Bacterial adhesion Infections Monosaccharides 2015 |
| Issue Date: | Aug-2015 |
| Publisher: | Royal Society of Chemistry |
| Citation: | Chemical Communications, 51(86),15669-15672. |
| Abstract: | Achieving selective and sensitive carbohydrate-protein interactions (CPIs) using nanotechnology is an intriguing area of research. Here we demonstrate that the different shapes of gold nanoparticles (AuNPs) functionalized with monosaccharides tune the bacterial aggregations. The mechanism of aggregation revealed that the large number of surface interactions of rod shaped mannose-AuNPs with E. coli ORN 178 compared with spherical and star-shaped AuNPs exhibited higher avidity and sensitivity. Moreover, such sensitive binding can be used for effective inhibition of bacterial infection of cells. |
| URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2163 https://doi.org/10.1039/C5CC05238F |
| ISSN: | 1359-7345 1364-548X |
| Appears in Collections: | JOURNAL ARTICLES |
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