Please use this identifier to cite or link to this item:
http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2380| Title: | Facile Buchwald-Hartwig coupling of sterically encumbered substrates effected by PNP ligands |
| Authors: | KATHEWAD, NEHA ANAGHA, M. C. PARVIN, NASRINA Parambath, Sneha Parameswaran, Pattiyil KHAN, SHABANA Dept. of Chemistry |
| Keywords: | Palladium-catalyzed amination Aryl halides C-N Scalable synthesis Carbon Bromides Efficient Arylamines Phosphines Complexes TOC-MAR-2019 2019 |
| Issue Date: | Jan-2019 |
| Publisher: | Royal Society of Chemistry |
| Citation: | Dalton Transactions, 48(8), 2730-2734. |
| Abstract: | The diphosphinoamine ligands [(Ph2P)2N(Ar); 1 (Ar = C6H5), 2 (Ar = 2,6-iPr2C6H3)] were effectively utilized in Buchwald–Hartwig coupling of a range of sterically demanding substrates. The reaction was carried out using conventional and microwave routes and the latter reduces the reaction time from 3 d to 15–30 min. A broad substrate scope was achieved in this protocol and most of the coupling products are isolated on a mutligram scale. DFT calculations were carried out to elucidate the reaction mechanism. |
| URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2380 https://doi.org/10.1039/c9dt00159j |
| ISSN: | 1477-9226 1477-9234 |
| Appears in Collections: | JOURNAL ARTICLES |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.