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http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2498| Title: | Ruthenium-catalyzed direct α-alkylation of amides using alcohols |
| Authors: | CHAUDHARI, MORESHWAR B. BISHT, GIRISH SINGH KUMARI, POOJA GNANAPRAKASAM, BOOPATHY Dept. of Chemistry |
| Keywords: | Ruthenium-catalyzed Direct ?-alkylation Pharmaceutical compounds Ru-PNN catalyst NMR and mass analysis 2016 |
| Issue Date: | Sep-2016 |
| Publisher: | Royal Society of Chemistry |
| Citation: | Organic and Biomolecular Chemistry, 14(39), 9215-9220. |
| Abstract: | The highly efficient direct α-alkylation of unactivated amides has been accomplished using alcohols in the presence of the Ru-PNN catalyst (0.1 mol%) with a high turnover number. Using this approach, 2-oxindole was directly transformed into C3-alkylated 3-hydroxyindolin-2-one in one step without the use of any oxidant. |
| URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2498 https://doi.org/10.1039/C6OB01786J |
| ISSN: | 1477-0520 1477-0539 |
| Appears in Collections: | JOURNAL ARTICLES |
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