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Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2622
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dc.contributor.authorMeesala, Srinuen_US
dc.contributor.authorLakwal, Vijay R.en_US
dc.contributor.authorKharate, Dinesh S.en_US
dc.contributor.authorMokashe, Satish S.en_US
dc.contributor.authorWATVE, MILINDen_US
dc.date.accessioned2019-04-29T09:21:00Z
dc.date.available2019-04-29T09:21:00Z
dc.date.issued2016-08en_US
dc.identifier.citationJournal of Chemical, Biological and Physical Sciences, 6(4), 1400-1418.en_US
dc.identifier.issn2249 -1929en_US
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2622-
dc.identifier.uri-en_US
dc.description.abstractA novel benzofuran sesquiterpene derivative:7-methyl-7-((E)-4-methylpenta1,3-dien-1-yl)-5,6,7,7a-tetrahydrobenzofuran-3a(4H)-ol(Iricinol A), was isolated from a marine sponge Ircinia fusca (Carter, 1880). The structure of the compound was elucidated by using 1D, 2DNMR, and ESI-MS-TOF. The compound showed broad-spectrum activity against bacteria and fungi at 2 µg/µL. Also, it exhibited in vitro cytotoxic activity against RAW264.7 cells (mouse monotype macrophage leukemia) and N2A cells (neuroblastoma) with IC50 values 55 ± 4.21 µg/mL.en_US
dc.language.isoenen_US
dc.publisherJCBPSCen_US
dc.subjectSpongeen_US
dc.subjectSesquiterpenesen_US
dc.subjectNMR & Mass spectrometryen_US
dc.subjectNatural Productsen_US
dc.subjectAntimicrobial anticancer activityen_US
dc.subjectMarine organismsen_US
dc.subject2016en_US
dc.titleIsolation and Characterization of Bioactive Benzofuran Sesquiterpene from Marine Sponge Ircinia Fusca (Carter, 1880)en_US
dc.typeArticleen_US
dc.contributor.departmentDept. of Biologyen_US
dc.identifier.sourcetitleJournal of Chemicalen_US
dc.publication.originofpublisherIndianen_US
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