Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2720
Title: Temperature-controlled redox-neutral ruthenium(II)-catalyzed regioselective allylation of benzamides with allylic acetates
Authors: Manikandan, Rajendran
JAYAKANNAN, MANICKAM
Dept. of Chemistry
Keywords: Temperature-controlled
Redox-neutral
Allylic acetates
Ortho-Allyl and vinylated benzamides
2016
Issue Date: Jun-2016
Publisher: Royal Society of Chemistry
Citation: Organic and Biomolecular Chemistry, 14(32), 7691-7701.
Abstract: Substituted aromatic amides reacted efficiently with allylic acetates in the presence of a cationic ruthenium complex in ClCH2CH2Cl at room temperature providing ortho allylated benzamides in a highly regioselective manner without any oxidant and base. The whole catalytic reaction occurred in a Ru(II) oxidation state and thus the oxidation step is avoided. By tuning the reaction temperature, ortho allyl and vinyl benzamides were prepared exclusively. Later, ortho allyl and vinylated benzamides were converted into biologically useful six- and five-membered benzolactones in the presence of HCl.
URI: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2720
https://doi.org/10.1039/C6OB01498D
ISSN: 1477-0520
1477-0539
Appears in Collections:JOURNAL ARTICLES

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