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Title: | Synthesis and Enzymatic Incorporation of a Responsive Ribonucleoside Probe That Enables Quantitative Detection of Metallo-Base Pairs |
Authors: | MANNA, SUDESHNA SRIVATSAN, SEERGAZHI G. Dept. of Chemistry |
Keywords: | Chemistry TOC-JUN-2019 2019 |
Issue Date: | Jun-2019 |
Publisher: | American Chemical Society |
Citation: | Organic Letters, 21(12), 4646-4650. |
Abstract: | Synthesis of a highly responsive fluorescent ribonucleoside analogue based on a 5-methoxybenzofuran uracil core, enzymatic incorporation of its triphosphate substrate into RNA transcripts, and its utility in the specific detection and estimation of Hg2+-ion-mediated metallo-base pair formation in DNA–RNA and RNA–RNA duplexes are described. |
URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3108 https://doi.org/10.1021/acs.orglett.9b01544 |
ISSN: | 1523-7060 |
Appears in Collections: | JOURNAL ARTICLES |
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