Please use this identifier to cite or link to this item:
http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3126
Title: | Transmembrane H+/Cl- cotransport activity of bis(amido)imidazole receptors |
Authors: | SHINDE, SOPAN VALIBA TALUKDAR, PINAKI Dept. of Chemistry |
Keywords: | Anion Transport Ion Channels Prodigiosins Apoptosis PH Association Symporter Constants Membrane TOC-JUN-2019 2019 |
Issue Date: | May-2019 |
Publisher: | Royal Society of Chemistry |
Citation: | Organic & Biomolecular Chemistry, 17(18), 4483-4490. |
Abstract: | AA series of sickle-shaped bis(amido) imidazoles are synthesized for their ion transport studies. Proton–anion binding by the neutral and protonated form of receptors assessed by 1H-NMR titration experiments confirmed better chloride binding by the protonated form of a receptor compared to its neutral form. The transport experiments across unimolecular vesicles (by HPTS and lucigenin assays) confirmed the H+/Cl− symport process under the applied pH gradient conditions. The transporter also allows anion antiport as evident from the studies under symmetrical pH conditions. The ionophoric activity by the mobile carrier mechanism is proved by the U-tube experiment. |
URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3126 https://doi.org/10.1039/C9OB00554D |
ISSN: | 1477-0520 1477-0539 |
Appears in Collections: | JOURNAL ARTICLES |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.