Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3126
Title: Transmembrane H+/Cl- cotransport activity of bis(amido)imidazole receptors
Authors: SHINDE, SOPAN VALIBA
TALUKDAR, PINAKI
Dept. of Chemistry
Keywords: Anion Transport
Ion Channels
Prodigiosins
Apoptosis
PH
Association
Symporter
Constants
Membrane
TOC-JUN-2019
2019
Issue Date: May-2019
Publisher: Royal Society of Chemistry
Citation: Organic & Biomolecular Chemistry, 17(18), 4483-4490.
Abstract: AA series of sickle-shaped bis(amido) imidazoles are synthesized for their ion transport studies. Proton–anion binding by the neutral and protonated form of receptors assessed by 1H-NMR titration experiments confirmed better chloride binding by the protonated form of a receptor compared to its neutral form. The transport experiments across unimolecular vesicles (by HPTS and lucigenin assays) confirmed the H+/Cl− symport process under the applied pH gradient conditions. The transporter also allows anion antiport as evident from the studies under symmetrical pH conditions. The ionophoric activity by the mobile carrier mechanism is proved by the U-tube experiment.
URI: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3126
https://doi.org/10.1039/C9OB00554D
ISSN: 1477-0520
1477-0539
Appears in Collections:JOURNAL ARTICLES

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