Please use this identifier to cite or link to this item:
http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3490| Title: | Improvement of drug delivery by hyperthermia treatment using magnetic cubic cobalt ferrite nanoparticles |
| Authors: | Dey, Chaitali Baishya, Kaushik GHOSH, ARUP Goswami, Madhuri Mandal Ghosh, Ajay Mandal, Kalyan Dept. of Physics |
| Keywords: | Improvement of drug Magnetic nanoparticles Cobalt ferrite Magnetic hyperthermia Drug release 2017 |
| Issue Date: | Apr-2017 |
| Publisher: | Elsevier B.V. |
| Citation: | Journal of Magnetism and Magnetic Materials, 427, 168-174. |
| Abstract: | In this study, we report a novel synthesis method, characterization and application of a new class of ferromagnetic cubic cobalt ferrite magnetic nanoparticles (MNPs) for hyperthermia therapy and temperature triggered drug release. The MNPs are characterized by XRD, TEM, FESEM, AC magnetic hysteresis and VSM. These MNPs were coated with folic acid and loaded with an anticancer drug. The drug release studies were done at two different temperatures (37 °C and 44 °C) with progress of time. It was found that higher release of drug took place at elevated temperature (44 °C). We have developed a temperature sensitive drug delivery system which releases the heat sensitive drug selectively as the particles are heated up under AC magnetic field and controlled release is possible by changing the external AC magnetic field. |
| URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3490 https://doi.org/10.1016/j.jmmm.2016.11.024 |
| ISSN: | 0304-8853 |
| Appears in Collections: | JOURNAL ARTICLES |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.