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Title: | Exploring the effect of sialic acid orientation on ligand–receptor interactions |
Authors: | YADAV, ROHAN KIKKERI, RAGHAVENDRA Dept. of Chemistry |
Keywords: | Chemistry 2012 |
Issue Date: | May-2012 |
Publisher: | Royal Society of Chemistry |
Citation: | Chemical Communications, 48(58), 7265-7267. |
Abstract: | Here, we present the synthesis of two sialo-micelles to validate the significance of sialic acid orientation during specific carbohydrate–protein and carbohydrate–carbohydrate interactions. Our data clearly suggest that orientation of carboxylic acid and glycerol side chains of sialic acid moieties exert fine tuning of ligand–receptor interactions. |
URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3619 https://doi.org/10.1039/C2CC32587J |
ISSN: | 1359-7345 1364-548X |
Appears in Collections: | JOURNAL ARTICLES |
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