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http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5159| Title: | Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors |
| Authors: | DHARMARAJA, ALLIMUTHU T. Alvala, Mallika Sriram, Dharmarajan Yogeeswari, Perumal CHAKRAPANI, HARINATH Dept. of Chemistry |
| Keywords: | Chemistry 2012 |
| Issue Date: | Oct-2012 |
| Publisher: | Royal Society of Chemistry |
| Citation: | Chemical Communications, 48(83), 10325-10327. |
| Abstract: | Here, we report 5-hydroxy-1,2,3,4,4a,9a-hexahydro-1,4-ethano-9,10-anthraquinone (13), a small molecule generating reactive oxygen species (ROS) in pH 7.4 buffer under ambient aerobic conditions that has selective and potent Mycobacterium tuberculosis growth inhibitory activity. |
| URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5159 https://doi.org/10.1039/C2CC35343A |
| ISSN: | 1359-7345 1364-548X |
| Appears in Collections: | JOURNAL ARTICLES |
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