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Title: | BODIPY based 'click on' fluorogenic dyes: application in live cell imaging |
Authors: | CHAUHAN, DINESH PRATAPSINH SAHA, TANMOY LAHIRI, MAYURIKA TALUKDAR, PINAKI Dept. of Biology Dept. of Chemistry |
Keywords: | BODIPY Azide-alkyne click reaction Fluorescence Solvatochromic properties Cell imaging 2014 |
Issue Date: | Jan-2014 |
Publisher: | Elsevier B.V. |
Citation: | Tetrahedron Letters, 55(1), 244-247. |
Abstract: | The design, synthesis, and photophysical properties of new BODIPY-based fluorogenic ‘click on’ dyes are reported. CuAAC reaction of non-fluorescent BODIPY azide with a series of non-fluorescent alkyne molecules resulted in fluorescent triazoles which displayed up to 532-fold enhancement of fluorescence in the red region. Imaging studies confirmed the general trend of cell permeability and a cholesterol linked derivative exhibited selective localization into intracellular membranes. |
URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5231 https://doi.org/10.1016/j.tetlet.2013.11.003 |
ISSN: | 0040-4039 |
Appears in Collections: | JOURNAL ARTICLES |
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