Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5231
Title: BODIPY based 'click on' fluorogenic dyes: application in live cell imaging
Authors: CHAUHAN, DINESH PRATAPSINH
SAHA, TANMOY
LAHIRI, MAYURIKA
TALUKDAR, PINAKI
Dept. of Biology
Dept. of Chemistry
Keywords: BODIPY
Azide-alkyne click reaction
Fluorescence
Solvatochromic properties
Cell imaging
2014
Issue Date: Jan-2014
Publisher: Elsevier B.V.
Citation: Tetrahedron Letters, 55(1), 244-247.
Abstract: The design, synthesis, and photophysical properties of new BODIPY-based fluorogenic ‘click on’ dyes are reported. CuAAC reaction of non-fluorescent BODIPY azide with a series of non-fluorescent alkyne molecules resulted in fluorescent triazoles which displayed up to 532-fold enhancement of fluorescence in the red region. Imaging studies confirmed the general trend of cell permeability and a cholesterol linked derivative exhibited selective localization into intracellular membranes.
URI: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5231
https://doi.org/10.1016/j.tetlet.2013.11.003
ISSN: 0040-4039
Appears in Collections:JOURNAL ARTICLES

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