Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5360
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKinatukara, Priyadarshanen_US
dc.contributor.authorSINGH, SHUBHAMen_US
dc.contributor.authorMHETRE, AMOLen_US
dc.contributor.authorKAMAT, SIDDHESH S. et al.en_US
dc.date.accessioned2020-11-13T09:30:21Z
dc.date.available2020-11-13T09:30:21Z
dc.date.issued2020-11en_US
dc.identifier.citationTransgenic Research, 29, 553–562.en_US
dc.identifier.issn0962-8819en_US
dc.identifier.issn1573-9368en_US
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5360-
dc.identifier.urihttps://doi.org/10.1007/s11248-020-00219-6en_US
dc.description.abstractDisco-interacting protein 2 is a highly conserved three-domain protein with two tandem Adenylate-forming domains. It is proposed to influence the processes involved in neuronal development by influencing lipid metabolism and remains to be characterized. In this study, we show that Disco-interacting protein 2a null mice do not exhibit overt phenotype defects. However, the body composition differences were observed in these mice under different dietary regimens. The neutral lipid composition of two different diets was characterized, and it was observed that the new-born mice grow relatively slower than the wild-type mice with delayed appearance of features such as dentition when fed with high-triacylglycerol NIN-formulation diet. The high-diacylglycerol Safe-formulation diet was found to accumulate more fat mass in mice than those fed with high-triacylglycerol NIN-formulation diet beyond 10 months. These findings point to a proposed relationship between dietary components (particularly the lipid composition) and body composition along with the growth of neonates in mice lacking the gene Disco-interacting protein 2a.en_US
dc.language.isoenen_US
dc.publisherSpringer Natureen_US
dc.subjectDisco-interacting protein 2en_US
dc.subjectAdenylate-forming domainsen_US
dc.subjectLipid compositionen_US
dc.subjectDietary componentsen_US
dc.subject2020en_US
dc.subject2020-NOV-WEEK2en_US
dc.subjectTOC-NOV-2020en_US
dc.titlePeri-natal growth retardation rate and fat mass accumulation in mice lacking Dip2A is dependent on the dietary compositionen_US
dc.typeArticleen_US
dc.contributor.departmentDept. of Biologyen_US
dc.identifier.sourcetitleTransgenic Researchen_US
dc.publication.originofpublisherForeignen_US
Appears in Collections:JOURNAL ARTICLES

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.