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http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5982| Title: | Combined expression pattern of SATB family chromatin organizers as improved biomarker tool for cancer prognosis |
| Other Titles: | Evaluating progression and aggressiveness of cancer, e.g. colorectal cancer/colon adenocarcinoma, involves evaluating combined expression levels of special AT-rich sequence-binding protein (SATB)-1 and SATB-2 chromatin organizers (DWPI title) |
| Authors: | GALANDE, SANJEEV NAIK, RUTIKA |
| Keywords: | SATB-1 SATB-2 2020 |
| Issue Date: | Feb-2020 |
| Abstract: | The present invention provides an in-vitro process for profiling a combined expression pattern of SATB (special AT-rich sequence-binding protein-1) family chromatin organizers i.e. SATB-1 and SATB-2 as a biomarker tool for cancer prognosis to assess cancer aggressiveness and it progression in an array of cancer types. The combined expression pattern of SATB is established by the method of Kaplan Meier survival analysis of a dataset of patients from a plurality of cancer types. Further, the present invention provides a prognostic kit to evaluate the progression of cancer by using the combined expression pattern of SATB-1 and SATB-2 as a biomarker tool for cancer prognosis. |
| URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5982 |
| Appears in Collections: | PATENTS |
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