Synthesis and Evaluation of Small Molecules Targeting miRNA-21

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DC Field	Value	Language
dc.contributor.advisor	HOTHA, SRINIVAS	en_US
dc.contributor.author	DEVA NISHANTH, TIRUKOTI	en_US
dc.date.accessioned	2016-05-06T11:49:00Z
dc.date.available	2016-05-06T11:49:00Z
dc.date.issued	2016-05	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/642	-
dc.description.abstract	miRNA-21 (miR-21) plays vital role in many cancers, inflammation, cardiovascular diseases. Targeting miR-21 is challenging due to the lack of bio-resistant oligo antisense nucleotides. To overcome the problem, developments of small organic molecules which inhibit the biogenesis pathway of miRNA are sought. In this study, we came with small molecule peptoids that target miRNA-21 biogenesis pathway and looked at their efficacy by carrying biological studies using the MCF7 cancer cell line.	en_US
dc.language.iso	en	en_US
dc.subject	2016
dc.subject	Chemical Biology	en_US
dc.subject	miRNA-21	en_US
dc.title	Synthesis and Evaluation of Small Molecules Targeting miRNA-21	en_US
dc.type	Thesis	en_US
dc.type.degree	BS-MS	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.contributor.registration	20111064	en_US
Appears in Collections:	MS THESES

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