Three in One: Triple G-C-T Base-Coded Brahma Nucleobase Amino Acid: Synthesis, Peptide Formation, and Structural Features

Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/6448

Title:	Three in One: Triple G-C-T Base-Coded Brahma Nucleobase Amino Acid: Synthesis, Peptide Formation, and Structural Features
Authors:	Wagh, Mahendra A. MAITY, RAHUL Bhosale, Rohit J. Semwal, Divyam Tothadi, Srinu VAIDHYANATHAN, RAMANATHAN Sanjayan, Gangadhar J. Dept. of Chemistry
Keywords:	Nucleobases Nucleic acids Peptides and proteins Monomers Mixtures 2021-DEC-WEEK2 TOC-DEC-2021 2021
Issue Date:	Nov-2021
Publisher:	American Chemical Society
Citation:	Journal of Organic Chemistry, 86(21), 15689–15694.
Abstract:	This note reports the synthesis and peptide formation of a novel triple G-C-T nucleobase amino acid (NBA) building block featuring three recognition faces: DDA (G mimic), DAA (C mimic), and ADA (T mimic). Readily obtainable in multigram scale in a remarkably easy one-step reaction, this unique NBA building block offers scope for wide ranging applications for nucleic acid recognition and nucleic acid peptide/protein interaction studies.
URI:	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/6448 https://doi.org/10.1021/acs.joc.1c01228
ISSN:	0022-3263 1520-6904
Appears in Collections:	JOURNAL ARTICLES

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