Please use this identifier to cite or link to this item:
http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/7029| Title: | A convenient route to synthesize N2-(isobutyryl)-9-(carboxymethyl)guanine for aeg-PNA backbone |
| Authors: | DATTA, DHRUBAJYOTI Dept. of Chemistry |
| Keywords: | Chemistry 2020 |
| Issue Date: | Aug-2020 |
| Publisher: | Taylor & Francis |
| Citation: | Nucleosides, Nucleotides & Nucleic Acids, 39(4) , 530-541. |
| Abstract: | Synthesis of exclusive N2-(isobutyryl)-9-(carboxymethyl)guanine, an important moiety for peptide nucleic acid synthesis has been reported through a high-yielding reaction scheme starting from 6-chloro-2-amino purine. Crystal structures of two intermediates confirmed the formation of N9-regioisomer. This new synthetic route can potentially replace the conventional tedious method with moderate overall yield. |
| URI: | https://doi.org/10.1080/15257770.2019.1666139 http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/7029 |
| ISSN: | 1525-7770 1532-2335 |
| Appears in Collections: | JOURNAL ARTICLES |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.