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http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/7611| Title: | Assay for Determining Target Engagement in Real-Time in Living Systems |
| Authors: | BRITTO, SANDANARAJ S. BATHLA, PUNITA De, Abhijit Mujawar, Aaiyas |
| Keywords: | Biology Chemistry Patent |
| Issue Date: | Jun-2022 |
| Abstract: | The present disclosure relates to an assay for determining drug-target engagement in real-time. Specifically, the present disclosure provides a method for determining drug candidate-target interaction in real-time in living systems using Activity-based Reporter Gene Technology - Bioluminescence Resonance Energy Transfer (AbRGT-BRET) based assay. The said assay is useful for High Throughput Screening of compounds to a specific target. |
| URI: | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/7611 |
| Appears in Collections: | PATENTS |
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