Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/7611
Title: Assay for Determining Target Engagement in Real-Time in Living Systems
Authors: BRITTO, SANDANARAJ S.
BATHLA, PUNITA
De, Abhijit
Mujawar, Aaiyas
Keywords: Biology
Chemistry
Patent
Issue Date: Jun-2022
Abstract: The present disclosure relates to an assay for determining drug-target engagement in real-time. Specifically, the present disclosure provides a method for determining drug candidate-target interaction in real-time in living systems using Activity-based Reporter Gene Technology - Bioluminescence Resonance Energy Transfer (AbRGT-BRET) based assay. The said assay is useful for High Throughput Screening of compounds to a specific target.
URI: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/7611
Appears in Collections:PATENTS

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