Please use this identifier to cite or link to this item:
Title: Design and Synthesis of Novel Organic Probes towards Early-Stage Detection of Amyloid Fibrils and Their Mechanistic Role in Protein Misfolding Disease
Dept. of Chemistry
Keywords: Biophysics
Issue Date: Dec-2023
Citation: 123
Abstract: The main motivation of all the works containing in the thesis is design and synthesis of novel organic molecules for early-stage detection of amyloid fibrils and their mechanistic role in protein misfolding disease, such as Alzheimer’s, Parkinson’s disease and prion’s disease. The early-stage species generated in the pathway of aggregation of A-42 and -synuclein known as main culprits for several neurological disorder, therefore systematic efforts at devising new fluorescent molecular probes and drug molecules are indispensable to estimate and modulate the mechanism of its formation
Appears in Collections:PhD THESES

Files in This Item:
File Description SizeFormat 
20173509_Aslam_Uddin_PhD_Thesis.pdfPhD Thesis10.07 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.