Please use this identifier to cite or link to this item: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/8380
Title: BoneXpert-derived bone health index reference curves constructed on healthy Indian children and adolescents
Authors: Oza, Chirantap
Misha Antani
Mondkar, Shruti A.
Kajale,Neha
Ojha, Vikas
GOEL, PRANAY
Khadilkar, Vaman
Khadilkar, Anuradha V.
Dept. of Biology
Keywords: Artificial intelligence
Bone health index
Children
India
Lambda-mu-sigma
Reference data
2023-DEC-WEEK3
TOC-DEC-2023
2024
Issue Date: Jan-2024
Publisher: Springer Nature
Citation: Pediatric Radiology, 54, 127–135.
Abstract: Background -Artificial intelligence (AI)-based applications for the assessment of the paediatric musculoskeletal system like BoneXpert are not only useful to assess bone age (BA) but also to provide a bone health index (BHI) and a standard deviation score (SDS) for both. This allows comparison of the BHI with age- and sex-matched healthy Caucasian children. Objective-We conducted this study with the objective of generating BHI curves using BoneXpert in healthy Indian children with BA between 2 and 17 years. Method - We retrospectively reviewed anthropometric parameters, BHI, and BHI SDS data of digitalized left-hand radiographs (joint photographic experts group [jpg] format) of a cohort of 788 paediatric patients from a previous study to which they were recruited to compare various methods of BA assessment. The recruited children represented all age groups for both sexes. The corrected BHI for jpg images was calculated using the formula corrected BHI=BHI*(stature/(avL*50))^0.33333 where stature is height of subject and avL is average length of metacarpal bones. The reference Indian BHI curves and centiles were generated using the Lambda-Mu-Sigma method. Result-The mean BHI and BHI SDS of the study group were 4.02±0.57 and −1.73±1.09, respectively. The average increase in median BHI from each age group was between 2.5% and 3% in both sexes up to age of 14 years after which it increased to 4.5% to 5%. The mean BHI of Indian children was lower than that of Caucasian children with maximum differences noted in boys at 16 years (21.7%) and girls at 14 years (16%). We report 8.4% SD of BHI for our study sample. Reference percentile curves for BHI according to BA were derived separately for boys and girls.
URI: https://doi.org/10.1007/s00247-023-05824-1
http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/8380
ISSN: 1432-1998
Appears in Collections:JOURNAL ARTICLES

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