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http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/838Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | Cynthia He | en_US |
| dc.contributor.author | KATTI, ADITYA | en_US |
| dc.date.accessioned | 2018-04-23T03:26:23Z | |
| dc.date.available | 2018-04-23T03:26:23Z | |
| dc.date.issued | 2017-03 | en_US |
| dc.identifier.uri | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/838 | - |
| dc.description.abstract | Membrane dynamics of Procyclin, a GPI-anchored protein in Trypanosoma brucei has been studied for the first time by z-scan FCS and FCS Diffusion Laws. The τ0 for procyclin is ~6.8 ms which indicates a cholesterol-dependent nanodomain confinement which on depletion by MβCD gives a τ0 of ~1.6 ms and is ~2.1 ms at 24 hours post CC2D-RNAi and reduces further to ~0.6 ms at 48 hours post CC2D-RNA interference. Dynamics after knockdown of CC2D by RNA interference resembles cholesterol depletion by MβCD on plasma membrane of Trypanosoma brucei. | en_US |
| dc.language.iso | en | en_US |
| dc.subject | 2017 | |
| dc.subject | Physics | en_US |
| dc.subject | Membrane dynamics | en_US |
| dc.subject | Plasma membrane | en_US |
| dc.subject | FCS Diffusion Laws | en_US |
| dc.subject | Trypanosoma brucei | en_US |
| dc.title | Membrane dynamics of Procyclin and effect of CC2D on plasma membrane of Trypanosoma brucei by z-scan FCS and FCS Diffusion Laws | en_US |
| dc.type | Thesis | en_US |
| dc.type.degree | BS-MS | en_US |
| dc.contributor.department | Interdisciplinary | en_US |
| dc.contributor.registration | 20121092 | en_US |
| Appears in Collections: | MS THESES | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 20121092_Aditya_Katti.pdf | 1.5 MB | Adobe PDF | View/Open |
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