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NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell

Desai, Sagar J.; Upadhya, Manoj A.; SUBHEDAR, NISHIKANT K.; Kokare, Dadasaheb M. (Elsevier B.V., 2013-06)

Although the interaction between endogenous neuropeptide Y (NPY) and opioidergic systems in processing of reward has been speculated, experimental evidence is lacking. We investigated the role of NPY, and its Y1 receptors, ...
A simple and economical method of electrode fabrication for brain self-stimulation in rats

Desai, Sagar J.; Bharne, Ashish P.; Upadhya, Manoj A.; Somalwar, Amita R.; SUBHEDAR, NISHIKANT K.; Kokare, Dadasaheb M. (Elsevier B.V., 2014-04)

ntracranial self-stimulation (ICSS) is an operant paradigm in which rodents self-administer rewarding electrical stimulation through electrodes implanted into the brain. We describe a simple, inexpensive and reliable method ...
Neuropeptide Y attenuates anxiety- and depression-like effects of cholecystokinin-4 in mice

Desai, Sagar J.; Borkar, C.D.; Nakhate, Kartik T.; SUBHEDAR, NISHIKANT K.; Kokare, Dadasaheb M. (Elsevier B.V., 2014-09)

We investigated the involvement of neuropeptide Y (NPY) in the modulation of cholecystokinin-4 (CCK-4)-evoked anxiety and depression. Adult male mice were injected with vehicle, CCK-4, NPY, NPY Y1 receptor agonist [Leu31, ...

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