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Integrated promoter-capture Hi-C and Hi-C analysis reveals fine-tuned regulation of the 3D chromatin architecture in colorectal cancer

SAW, AJAY KUMAR; MADHOK, AYUSH; Bhattacharya,Anupam; Nandi,Soumyadeep; GALANDE, SANJEEV (Frontiers, 2025-03)

Hi-C is a widely used technique for mapping chromosomal interactions within a 3D genomic framework, however, its resolution is often constrained by sequencing depth, making it challenging to detect fine-scale interactions. ...
A randomized phase II/III trial of rosuvastatin with neoadjuvant chemo-radiation in patients with locally advanced rectal cancer

GUPTA, EKTA; GALANDE, SANJEEV et. al. (Frontiers, 2025-03)

Statins have been shown to improve the possibility of a pathological complete response (pCR) in patients with locally advanced rectal cancer when given in combination with neo-adjuvant chemo-radiation (NACTRT) in observational ...

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