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  • KALE, GIRISH (2011-01)
    This study involves traction force microscopy related techniques for analyzing the process of neuronal growth cone dynamics in the context of axon guidance. The system that is used will allow measuring the forces exerted ...
  • CHOUHAN, NITIN SINGH (2011-06)
    Aggressive behavior is important for animals for survival and reproduction as it helps in getting access to necessities like food and mates. Therefore aggressive behavior can be considered as an indicative of fitness of ...
  • RAHUL, PASUPUREDDY (2012-05)
    Actin cytoskeletal regulation, a crucial feature of cellular remodeling, is a dynamic process and has been extensively investigated. Formins, a class of actin nucleators, have been demonstrated to actively regulate actin ...
  • PATTADKAL, JAGRUTI (2013-05)
    In this study, mechanical response features of neuronal cells subjected to tension are characterized using a home­built force apparatus. We find that axons, when subjected to increasing stress in a stepwise fashion, sh ...
  • BEERAKA, SAI PRASHANTH KUMAR (2014-05)
    Actin is involved in various aspects of cellular motility, including growth cone-dependent translocation and guidance of axons. During cellular motility actin is pivotal in generating protrusive structures, like filopodia ...
  • KANIGANTI, TARUN (2014-06)
    Changes in the brain activity patterns are the neural correlates underlying behavioural flexibility. Previous studies con ducted in our lab oratory have identified CART as a major anorexia inducing agent in zebrafish. ...
  • AKASH, G. (Journal of Comparative Neurology, 2014-07)
    Neural circuits of innate behaviors which are necessary for survival are redundant and hardwired as they are shaped by selective pressure. However, functional organization of these circuits is poorly understood. Here we ...
  • JACOB, AJESH (2015-05)
    The proper functioning of a mature nervous system depends on the complex neuronal circuits. One of the critical phases of neuronal development is the formation of specific connections between the neurons and their target. ...
  • LAKSHMI, P S (2016-05)
    Cytoplasmic dynein is a motor protein classically involved in transport of cargo towards the minus end of microtubules. This project focuses on the role of dynein in forward translocation of cytoskeletal meshwork in growth ...
  • GHORPADE, SMITA (2016-05)
    Formins are a family of proteins that are involved in nucleating and elongating actin filaments and are hence hypothesized to be involved in the development of nervous system. The project aims at studying the role of one ...
  • CHOKSI, BHAVIN (2018-04)
    Feeding is a complex behavior having a robust and conserved underlying neural circuitry. Different regions of the brain take part in regulating this behavior along with myriad signaling molecules like orexigenic ...
  • DAS, SOORAJ (2019-06)
    Axonal branching process is an essential mechanism for forming complex neural circuits by facilitating in the formation of multiple synaptic connections with multiple target-fields. Even though the axonal branching ...
  • PRAKASH, MANJARI (2019-12)
    Interconnected neural circuits give rise to behavior. For the formation of these neural circuits, axonal guidance during development is essential. Axonal guidance requires the remodelling of the actin ...
  • CHACKO, FEBA (2020-04)
    The body is a complex machine that consists of several subsystems working together to stay alive and reproduce. These subsystems and the resulting behaviours are regulated by the brain to best negotiate the changing ...
  • C. S., JAYAPRIYA (2020-06)
    Cytoskeletal remodelling is imperative for the formation of precise neural circuits. Formin2 (Fmn2) is a protein known to be involved in the remodelling of both actin and microtubule cytoskeletons. Fmn2 mRNA was previously ...
  • B, NIRANJAN (2022-05)
    CART (Cocaine- and amphetamine-regulated transcript) is a key neuropeptide involved in regulating various processes like food intake and energy homeostasis, reward and addiction, and learning and memory. Studies have also ...
  • SEWATKAR, LISAS (2022-05)
    Axon collateral branching is a ubiquitous mechanism during neurodevelopment. More recently, it has been implicated in regeneration in the adult nervous system. Cytoskeleton remodelling is an essential step in facilitating ...
  • PAGRUT, SAKSHI (2023-05)
    Axon collateral branching is a critical process that enables neurons to form complex neural circuits and exhibit neural plasticity. Collateral branching is a highly cytoskeletal-dependent process that is initiated by the ...
  • K DAVID, ANTONY KIRAN (2023-05)
    Larval Zebrafish respond to visual stimuli with eye saccades and tail flicks, which depend on the features of the stimuli. Any deficit in these responses indicates a possible defect in visual processing. Studies in the lab ...
  • AP, NIVED (2024-05)
    Evolution demanded not only the acute ability to detect and respond to threats but also the capability to learn from these encounters. The interactions between survival circuits and energy states in the brain, including ...

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