Overcoming drug resistance and improving the toxicity profile of drugs are major
challenges in cancer chemotherapy. Targeted delivery along with detouring of drugs to
cellular organelles and nano-vehicles have emerged ...
This project attempts to address the problem of asset pricing in a financial market, where the interest rates and volatilities exhibit regime switching. This is an extension of the Black-Scholes model. Studies of ...
We consider a relativistic system of fermions with time-dependent mass, in 1+1
space-time dimensions. We show that the state of this system immediately after a sudden quench, in which the mass is taken to zero, is a ...
Viscosity-enhancing polymers such as Polyacrylamide (PAM) are gaining traction as candidates for Enhanced Oil Recovery (EOR). This popularity encourages the computational study of PAM to understand its behavior under various ...
In spite of the multitude of studies that deal with the effect of fluctuating environments on bacterial populations, how fluctuations and complexity (multiple stresses silmultaneously) interact with each other is poorly ...
To extract any astronomical information from the data obtained with a detector, detail knowledge of detector response and proper calibration is imperative. In this thesis, I present results
obtained by carrying out ...
Multifunctional Metal-organic frameworks (MOFs) have been the theme of cutting
edge research in the modern era. Because of diversified structures, structural
tunability and targeted host-guest interactions in these porous ...
Precise activation of signaling pathways is essential for the development of a multicellular organism. Signaling systems display a high range of complexity with
quantitative differences in levels of activation often leading ...
Mitochondria synthesizes ATP which is the major source of cellular energy during oxidative phosphorylation in electron transport chain present in inner membrane of mitochondria. Previous studies showed the importance of ...
The orphan transporter, Vesicular Aminergic – Associated Transporter (VAAT/SLC10A4) was recently shown to have a modulatory role in monoaminergic and cholinergic signalling systems. These studies used constitutive knockout ...
Acoustic communication in animals generally serves many purposes including mate attraction and aggression. Males of tree crickets use acoustic communication to attract females. It has been observed that males of the tree ...
TopBP1 is an important mediator protein involved in the cell cycle checkpoint signaling pathway that is activated when there are single strand lesions on DNA. TopBP1 has structural and functional similarity to BRCA1 (a ...
Graphene and few layer graphene (thin-layer graphite) are important materials for a variety of potential applications. Large-scale growth of these materials is an area of growing interest and is proven to be challenging. ...
Aromatic heterocyclic rings are the backbone of various natural products and biologically active compounds. And, these compounds are made up of carbon-carbon or carbon-heteroatom bonds. Transition metal catalysed reactions ...
Recently, localized surface plasmon resonance (LSPR) has been observed in doped semiconductor nanocrystals (NCs), with distinct differences compared to LSPR from metallic NCs. In our Sn4+-doped In2O3 NCs, commonly known ...
Formins are a family of proteins that are involved in nucleating and elongating actin filaments and are hence hypothesized to be involved in the development of nervous system. The project aims at studying the role of one ...
Apoptosis Inhibitor 5, Api5 is a nuclear protein which inhibits apoptosis upon growth factor deprival and is up regulated in various cancers. Api5 levels have been shown to be cell cycle regulated. Role of Api5 in cellular ...
A problem frequently encountered in all disciplines of science is to obtain all the solutions
for a system of non-linear equations. A similar problem exists for reaction systems
with many reactants, products, and ...