Strand separation by negative supercoiling of B-DNA is known to give rise to noncanonical DNA structures. It is hypothesized that negative supercoiling might give rise to the formation of G-quadruplexes. Current literature ...
Earth-directed solar Coronal Mass Ejections (CMEs) often interact with the magnetosphere, causing geomagnetic storms that disrupt a range of technologies we routinely rely on. A good understanding of the CME-magnetosphere ...
Our efforts towards a chiral pool synthesis of (-)-brasilenol from (-)-β-pinene is reported here. Starting from relatively abundant (-)-β-pinene, the unnatural enantiomer (-)-brasilenol was targeted in 11 steps. Use of ...
This thesis aims to provide an overview of the Integro-differential equations of fractional type and the associated regularity results for the viscosity solution. In the second part of the thesis, we consider a nonlocal ...
Cholesterol and cholesteryl esters form the major sterol component of an animal cell. While there are extensive studies on understanding protein-cholesterol interactions, the protein interactors of cholesteryl esters mostly ...
Stimuli-responsive polymers are promising materials that aim to mimic the adaptive responses of biological systems like proteins, which respond to changes in pH, oxidation, and other stimuli. Polypeptides stand out because ...
Cytokinesis in eukaryotes includes assembly, constriction, and disassembly of the contractile ring (CR). Failure in any of these can lead to polyploidy and tumour formation. Fission yeast has been widely used as a model ...
Exponential reduction in Lithium reserves is an alarming indicator for requirement of alternate energy storage solutions to reduce the dependency on Lithium-ion Batteries. Sodium-ion batteries are considered as the ...
Antibiotic resistance poses a significant threat to public health, necessitating the development of alternative antimicrobial agents. Antimicrobial peptides (AMPs) have emerged as promising candidates due to their ...
Salmonella enterica is a common foodborne pathogen with diverse serovars exhibiting different host specificities and disease manifestations. The molecular mechanisms of Salmonella pathogenesis have been extensively studied ...
One of the fundamental axioms of quantum mechanics is that observables are self-adjoint or Hermitian operators in a complex Hilbert space. What started as a mathematical curiosity in the late 90s, theoretical investigations ...
This study investigates the nuances of the effects of free-stream turbulence (FST) on bluff bodies using a method that blends computational fluid dynamics (CFD) simulations and synthetic turbulence generation techniques. ...
Cellular differentiation into various tissues is a critical developmental feature of multi- cellular organisms. One of the key gene regulatory processes that play a vital role in tissue differentiation is RNA splicing. ...
In this thesis, we estimate the average ground state energy of spin glass models. Despite decades of study, there have been no exact explicit calculations for a mean field model of spin glass with finite ranged interactions. ...
In this thesis, we aim to study the Polya -Szego conjecture, which states that the regular polygon with n sides and fixed area minimizes the first Dirichlet eigenvalue among the family of simple polygons with $n$ sides in ...
Tellurene, a single layer of tellurium atoms arranged in a zig-zag chain structure, is a recent addition to the family of 2D materials. It has a trigonal crystal lattice with inherent structural anisotropy. Tellurene has ...
Integrin-mediated cell-matrix adhesion is known to regulate cell growth and survival, which is deregulated in transformed cancer cells that acquire the ability to grow without adhesion, becoming anchorage-independent. ...
Plants have a remarkable capacity for wound-healing and regeneration, which can be investigated easily in Arabidopsis thaliana. Regenerative responses in Arabidopsis are broadly categorized as tissue culture-induced, or ...
Plant response to herbivory has been extensively studied using folivore as a model system. Plants exhibit various defense strategies in response to folivore attacks to protect and prevent themselves from further attacks. ...
This study investigates the morphological classifications of galaxies in the early universe by employing the capabilities of Morpheus, a deep learning framework, in conjunction with the UNCOVER and CANDELS datasets from ...