A Mn(iii)-catalysed domino process for C-3 substituted dihydrocoumarins from 2-hydroxybenzyl alcohols and 4-hydroxy-2H-chromen-2-ones

Abstract

A Mn-catalysed efficient domino process for the synthesis of new C-3 substituted dihydrocoumarins from 2-hydroxybenzyl alcohols and 4-hydroxy-2H-chromen-2-ones under one-pot conditions is described. This reaction proceeds via a series of reactions in one-pot, such as o-quinone methide formation, Michael addition, intramolecular transesterification, and skeletal rearrangement to access dihydrocoumarins.