Anion Selective Ion Channel Constructed from a Self-Assembly of Bis(cholate)-Substituted Fumaramide

Roy, Arundhati; TALUKDAR, PINAKI; Malla, Javid Ahmad

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dc.contributor.author	Malla, Javid Ahmad	en_US
dc.contributor.author	Roy, Arundhati	en_US
dc.contributor.author	TALUKDAR, PINAKI	en_US
dc.date.accessioned	2018-10-29T08:59:36Z
dc.date.available	2018-10-29T08:59:36Z
dc.date.issued	2018-10	en_US
dc.identifier.citation	Organic Letters Vol. 20(19)	en_US
dc.identifier.issn	1523-7060	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1328
dc.identifier.uri	https://doi.org/10.1021/acs.orglett.8b02115	en_US
dc.description.abstract	The self-assembled ion channel constructed from bis(cholate)-substituted fumaramide is reported. Such ion channel formation was favored by intermolecular hydrogen bonding interactions among fumaramide moieties. Fluorescence kinetics experiments and planar bilayer conductance measurements confirmed the selective chloride transport through the channel. Theoretical calculations were done to confirm the hydrogen bonded self-assembly of fumaramides and chloride recognition within the cavity.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.subject	Apoptosis-Inducing Activity	en_US
dc.subject	Chloride Transport	en_US
dc.subject	Angstrom Resolution	en_US
dc.subject	Cholic-Acid	en_US
dc.subject	Membrane	en_US
dc.subject	Cells	en_US
dc.subject	Catalysis	en_US
dc.subject	Peptide	en_US
dc.subject	Barrels	en_US
dc.subject	TOC-OCT-2018	en_US
dc.subject	2018	en_US
dc.title	Anion Selective Ion Channel Constructed from a Self-Assembly of Bis(cholate)-Substituted Fumaramide	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Organic Letters	en_US
dc.publication.originofpublisher	Foreign	en_US