In situ, on-resin synthesis of 8-Br/NH2 adeninyl peptide nucleic acid (PNA) oligomers and complementation studies with DNA

dc.contributor.author	Vysabhattar, Raman	en_US
dc.contributor.author	GANESH, KRISHNA N.	en_US
dc.date.accessioned	2019-01-21T10:29:25Z
dc.date.available	2019-01-21T10:29:25Z
dc.date.issued	2010-12	en_US
dc.identifier.citation	Tetrahedron Letters, Vol. 50(51).	en_US
dc.identifier.issn	0040-4039	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1489
dc.identifier.uri	https://doi.org/10.1016/j.tetlet.2010.10.040	en_US
dc.description.abstract	A new, novel and efficient in situ synthesis of 8-aminoadeninyl PNA oligomers from corresponding 8-bromoadeninyl PNA oligomers is reported. The study of hybridisation properties of (8-Br/8-NH2) PNA oligomers with cDNA reveals substitution-site dependent stabilization of derived triplexes and duplexes.	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier B.V.	en_US
dc.subject	Peptide nucleic acid	en_US
dc.subject	Medicinal chemistry	en_US
dc.subject	DNA and RNA	en_US
dc.subject	Pyrimidine PNA sequence	en_US
dc.subject	Trifluoromethane sulphonic acid	en_US
dc.subject	2010	en_US
dc.title	In situ, on-resin synthesis of 8-Br/NH2 adeninyl peptide nucleic acid (PNA) oligomers and complementation studies with DNA	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Tetrahedron Letters	en_US
dc.publication.originofpublisher	Foreign	en_US