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Synthesis of the Antibacterial Benzoquinone Primin and its Water-Soluble Analogue, Primin Acid

Synthesis of the Antibacterial Benzoquinone Primin and its Water-Soluble Analogue, Primin Acid

Bhattacharya, Asish K.; Kaur, Tanpreet; GANESH, KRISHNA N.
URI: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1490
https://doi.org/10.1055/s-0029-1218666
Date: 2010-02


Abstract:

The biologically active natural product, primin and its water-soluble acid analogue, primin acid are prepared in 34% and 25% overall yields, respectively, from a common intermediate using a Grignard reaction and a Johnson-Claisen rearrangement as the key steps.

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