A Vinyl-Boronate Ester-Based Persulfide Donor Controllable by Hydrogen Peroxide, a Reactive Oxygen Species (ROS)

CHAKRAPANI, HARINATH; MANNA, SUMAN; BORA, PRERONA; Chauhan, Preeti

DR Home
→
PUBLICATIONS & PATENTS
→
JOURNAL ARTICLES
→
View Item

dc.contributor.author	BORA, PRERONA	en_US
dc.contributor.author	Chauhan, Preeti	en_US
dc.contributor.author	MANNA, SUMAN	en_US
dc.contributor.author	CHAKRAPANI, HARINATH	en_US
dc.date.accessioned	2019-01-24T09:14:14Z
dc.date.available	2019-01-24T09:14:14Z
dc.date.issued	2018-12	en_US
dc.identifier.citation	Organic Letters, Vol. 20(24) pp7916-7920.	en_US
dc.identifier.issn	1523-7060	en_US
dc.identifier.issn	1523-7052	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1554
dc.identifier.uri	https://doi.org/10.1021/acs.orglett.8b03471	en_US
dc.description.abstract	A vinyl boronate ester-based persulfidating agent that is selectively activated by hydrogen peroxide, which is a reactive oxygen species (ROS), and efficiently generated a persulfide by a hitherto unexplored 1,4-O,S-relay mechanism is reported. This donor was found to protect cells from cytotoxicity induced by oxidants, and the major byproduct is cinnamaldehyde, which is widely used in the food industry as an additive.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.subject	Small-Molecule	en_US
dc.subject	Mycobacterium-Tuberculosis	en_US
dc.subject	Equilibrium-Constants	en_US
dc.subject	Sulfide Protects	en_US
dc.subject	Chemical Biology	en_US
dc.subject	Keto-Enol	en_US
dc.subject	Disulfides	en_US
dc.subject	Generation	en_US
dc.subject	Activation	en_US
dc.subject	Precursors	en_US
dc.subject	TOC-JAN-2019	en_US
dc.subject	2018	en_US
dc.title	A Vinyl-Boronate Ester-Based Persulfide Donor Controllable by Hydrogen Peroxide, a Reactive Oxygen Species (ROS)	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Organic Letters	en_US
dc.publication.originofpublisher	Foreign	en_US