PNAs grafted with (α/γ, R/S)-aminomethylene pendants: Regio and stereo specific effects on DNA binding and improved cell uptake

dc.contributor.author	Mitrab, Roopa	en_US
dc.contributor.author	GANESH, KRISHNA N.	en_US
dc.date.accessioned	2019-02-14T05:49:14Z
dc.date.available	2019-02-14T05:49:14Z
dc.date.issued	2011-01	en_US
dc.identifier.citation	Chemical Communications, .47 (4), 1198-1200.	en_US
dc.identifier.issn	1359-7345	en_US
dc.identifier.issn	1364-548X	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1757
dc.identifier.uri	https://doi.org/10.1039/C0CC03988H	en_US
dc.description.abstract	PNAs grafted with cationic aminomethylene (am) pendants on the backbone at the glycyl (α) or ethylenediamine (γ) segments show regio (α/γ) and stereochemistry (R/S) dependent binding with complementary DNA. These are efficiently taken up by cells, with γ(S-am)aeg-PNA being the best in all properties.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.subject	PNAs grafted	en_US
dc.subject	DNA binding	en_US
dc.subject	Stereochemistry	en_US
dc.subject	ethylenediamine	en_US
dc.subject	2011	en_US
dc.title	PNAs grafted with (α/γ, R/S)-aminomethylene pendants: Regio and stereo specific effects on DNA binding and improved cell uptake	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Chemical Communications	en_US
dc.publication.originofpublisher	Foreign	en_US