Arylboronate Ester Based Diazeniumdiolates (BORO/NO), a Class of Hydrogen Peroxide Inducible Nitric Oxide (NO) Donors

CHAKRAPANI, HARINATH; RAVIKUMAR, GOVINDAN; DHARMARAJA, ALLIMUTHU T.

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dc.contributor.author	DHARMARAJA, ALLIMUTHU T.	en_US
dc.contributor.author	RAVIKUMAR, GOVINDAN	en_US
dc.contributor.author	CHAKRAPANI, HARINATH	en_US
dc.date.accessioned	2019-02-25T09:00:43Z
dc.date.available	2019-02-25T09:00:43Z
dc.date.issued	2014-05	en_US
dc.identifier.citation	Organic Letters, 16(10), 2610-2613.	en_US
dc.identifier.issn	1523-7060	en_US
dc.identifier.issn	1523-7052	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1927
dc.identifier.uri	https://doi.org/10.1021/ol5010643	en_US
dc.description.abstract	Here, we report the design, synthesis, and evaluation of arylboronate ester based diazeniumdiolates (BORO/NO), a class of nitric oxide (NO) donors activated by hydrogen peroxide (H2O2), a reactive oxygen species (ROS), to generate NO. We provide evidence for the NO donors’ ability to permeate bacteria to produce NO when exposed to H2O2 supporting possible applications for BORO/NO to study molecular mechanisms of NO generation in response to elevated ROS.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.subject	Arylboronate Ester	en_US
dc.subject	Diazeniumdiolates	en_US
dc.subject	Hydrogen Peroxide	en_US
dc.subject	Evaluation of arylboronate	en_US
dc.subject	Biological studies	en_US
dc.subject	Boronate ester protecting groups	en_US
dc.subject	2014	en_US
dc.title	Arylboronate Ester Based Diazeniumdiolates (BORO/NO), a Class of Hydrogen Peroxide Inducible Nitric Oxide (NO) Donors	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Organic Letters	en_US
dc.publication.originofpublisher	Foreign	en_US