A fluorescent off–on NBD-probe for F− sensing: theoretical validation and experimental studies

Datar, Avdhoot; Roy, Arundhati; KAND, DNYANESHWAR; Saha, Tanmoy; TALUKDAR, PINAKI

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dc.contributor.author	Roy, Arundhati	en_US
dc.contributor.author	Datar, Avdhoot	en_US
dc.contributor.author	KAND, DNYANESHWAR	en_US
dc.contributor.author	Saha, Tanmoy	en_US
dc.contributor.author	TALUKDAR, PINAKI	en_US
dc.date.accessioned	2019-02-25T09:26:08Z
dc.date.available	2019-02-25T09:26:08Z
dc.date.issued	2014-01	en_US
dc.identifier.citation	Organic and Biomolecular Chemistry, 12(13), 2143-2149 .	en_US
dc.identifier.issn	1477-0520	en_US
dc.identifier.issn	1477-0539	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2101
dc.identifier.uri	https://doi.org/10.1039/C3OB41886C	en_US
dc.description.abstract	The design, synthesis and fluoride sensing ability of a 7-nitro-2,1,3-benzoxadiazole (NBD) based chemodosimeter is reported. Theoretical calculations were used to design a more applicable off–on response, by choosing NBD as the accurate fluorophore. Reaction of the NBD-probe with 300 equivalents of tetrabutyl ammonium fluoride (TBAF) exhibited a response time of 80 minutes and the reaction was selective to F− and sensing of the ion was marked by a 110-fold enhancement of green fluorescence. The off–on fluorescence characteristics of the probe enabled its application in live-cell imaging of intracellular F− ions.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.subject	Experimental studies	en_US
dc.subject	F? sensing	en_US
dc.subject	Cell imaging	en_US
dc.subject	Ammonium fluoride	en_US
dc.subject	2014	en_US
dc.title	A fluorescent off–on NBD-probe for F− sensing: theoretical validation and experimental studies	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Organic and Biomolecular Chemistry	en_US
dc.publication.originofpublisher	Foreign	en_US