A convenient protocol for the deprotection of N-benzyloxycarbonyl (Cbz) and benzyl ester groups

dc.contributor.author	SULTANE, PRAKASH R.	en_US
dc.contributor.author	Mete, Trimbak B.	en_US
dc.contributor.author	BHAT, RAMAKRISHNA G.	en_US
dc.date.accessioned	2019-03-15T11:22:37Z
dc.date.available	2019-03-15T11:22:37Z
dc.date.issued	2015-04	en_US
dc.identifier.citation	Tetrahedron Letters, 56(16), 2067-2070.	en_US
dc.identifier.issn	0040-4039	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2139
dc.identifier.uri	https://doi.org/10.1016/j.tetlet.2015.02.131	en_US
dc.description.abstract	We describe a convenient and practical method for the deprotection of N-benzyloxycarbonyl (Cbz) and benzyl ester groups using NaBH4 and catalytic Pd–C in methanol. Deprotection was very facile and rapid. In situ generation of hydrogen is certainly user friendly and avoids the use of a hydrogen cylinder. In order to establish the wider applicability of this approach, deprotection has also been demonstrated in gram scale reactions	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier B.V.	en_US
dc.subject	Natural products	en_US
dc.subject	Amino acids	en_US
dc.subject	Deprotection	en_US
dc.subject	Hydrogenolysis	en_US
dc.subject	Practicability	en_US
dc.subject	2015	en_US
dc.title	A convenient protocol for the deprotection of N-benzyloxycarbonyl (Cbz) and benzyl ester groups	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Tetrahedron Letters	en_US
dc.publication.originofpublisher	Foreign	en_US