Propargyl 1,2-Orthoesters for a Catalytic and Stereoselective Synthesis of Pyrimidine Nucleosides

dc.contributor.author	Rao, Boddu Venkateswara	en_US
dc.contributor.author	Manmode, Sujit	en_US
dc.contributor.author	HOTHA, SRINIVAS	en_US
dc.date.accessioned	2019-03-15T11:22:38Z
dc.date.available	2019-03-15T11:22:38Z
dc.date.issued	2015-02	en_US
dc.identifier.citation	Journal of Organic Chemistry, 80 (3),1499-1505.	en_US
dc.identifier.issn	1499-1505	en_US
dc.identifier.issn	1520-6904	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2155
dc.identifier.uri	https://doi.org/10.1021/jo502413z	en_US
dc.description.abstract	Pyrimidine nucleosides are synthesized by using propargyl 1,2-orthoesters and Au(III) salt as a catalyst. Strategically positioned 1,2-orthoesters are found to yield only 1,2-trans nucleosides and enable preparation of 2′-OH containing pyrimidine nucleosides. The glycosyl donor employed in this study is stable and easily accessible. The identified high-yielding protocol is mild, diastereoselective, and catalytic.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.subject	Catalytic and Stereoselective	en_US
dc.subject	Catalytic and Stereoselective	en_US
dc.subject	High-yielding protocol	en_US
dc.subject	2015	en_US
dc.title	Propargyl 1,2-Orthoesters for a Catalytic and Stereoselective Synthesis of Pyrimidine Nucleosides	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Journal of Organic Chemistry	en_US
dc.publication.originofpublisher	Foreign	en_US