Synthesis of isoindolinones via a ruthenium-catalyzed cyclization of N-substituted benzamides with allylic alcohols

dc.contributor.author	Manoharan, Ramasamy	en_US
dc.contributor.author	JEGANMOHAN, MASILAMANI	en_US
dc.date.accessioned	2019-03-15T11:24:15Z
dc.date.available	2019-03-15T11:24:15Z
dc.date.issued	2015-01	en_US
dc.identifier.citation	Chemical Communications, 51(14), 2929-2932.	en_US
dc.identifier.issn	6111-6114	en_US
dc.identifier.issn	1364-548X	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2211
dc.identifier.uri	https://doi.org/10.1039/C4CC09877C	en_US
dc.description.abstract	N-Substituted aromatic and heteroaromatic amides reacted with substituted allylic alcohols in the presence of a ruthenium catalyst, AgSbF6 and a Cu(OAc)2·H2O oxidant, affording 3-substituted isoindolinone derivatives with diverse substituents in good to excellent yields. A possible reaction mechanism involving a five-membered ruthenacycle intermediate was proposed and strongly supported by experimental evidence.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.subject	Synthesis of isoindolinones	en_US
dc.subject	Catalyzed cyclization	en_US
dc.subject	N-substituted benzamides	en_US
dc.subject	Allylic alcohols	en_US
dc.subject	Isoindolinone core	en_US
dc.subject	2015	en_US
dc.title	Synthesis of isoindolinones via a ruthenium-catalyzed cyclization of N-substituted benzamides with allylic alcohols	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Chemical Communications	en_US
dc.publication.originofpublisher	Foreign	en_US