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Role of MADF BESS Domain Protein Family In Gene Regulation and Wing Development in Drosophila melanogaster
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| dc.contributor.advisor | RATNAPARKHI, GIRISH S. | en_US |
| dc.contributor.author | KULKARNI, APURV | en_US |
| dc.date.accessioned | 2013-05-14T10:32:07Z | |
| dc.date.available | 2013-05-14T10:32:07Z | |
| dc.date.issued | 2013-05 | en_US |
| dc.identifier.uri | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/269 | |
| dc.description.abstract | In Drosophila melanogaster, there are 16 genes listed in the MADF-BESS domain family. Three out of these sixteen genes -- hinge1 (CG9437), hinge2 (CG13897) and hinge3 (CG8359) -- have been shown to give a bent wing phenotype when knocked down by RNA interference. I have characterized the phenotype that results from knock down of hinge1 using flight assays, light microscopy and scanning electron microscopy. I found out that hinge1, hinge2 and hinge3 are negative regulators of wingless, the best characterized wnt gene in Drosophila melanogaster. | en_US |
| dc.language.iso | en | en_US |
| dc.subject | 2013 | |
| dc.subject | Developmental Biology | en_US |
| dc.title | Role of MADF BESS Domain Protein Family In Gene Regulation and Wing Development in Drosophila melanogaster | en_US |
| dc.type | Thesis | en_US |
| dc.type.degree | BS-MS | en_US |
| dc.contributor.department | Dept. of Biology | en_US |
| dc.contributor.registration | 20081010 | en_US |
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MS THESES [1705]
Thesis submitted to IISER Pune in partial fulfilment of the requirements for the BS-MS Dual Degree Programme/MSc. Programme/MS-Exit Programme