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Role of MADF BESS Domain Protein Family In Gene Regulation and Wing Development in Drosophila melanogaster

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dc.contributor.advisor RATNAPARKHI, GIRISH S. en_US
dc.contributor.author KULKARNI, APURV en_US
dc.date.accessioned 2013-05-14T10:32:07Z
dc.date.available 2013-05-14T10:32:07Z
dc.date.issued 2013-05 en_US
dc.identifier.uri http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/269
dc.description.abstract In Drosophila melanogaster, there are 16 genes listed in the MADF-BESS domain family. Three out of these sixteen genes -- hinge1 (CG9437), hinge2 (CG13897) and hinge3 (CG8359) -- have been shown to give a bent wing phenotype when knocked down by RNA interference. I have characterized the phenotype that results from knock down of hinge1 using flight assays, light microscopy and scanning electron microscopy. I found out that hinge1, hinge2 and hinge3 are negative regulators of wingless, the best characterized wnt gene in Drosophila melanogaster. en_US
dc.language.iso en en_US
dc.subject 2013
dc.subject Developmental Biology en_US
dc.title Role of MADF BESS Domain Protein Family In Gene Regulation and Wing Development in Drosophila melanogaster en_US
dc.type Thesis en_US
dc.type.degree BS-MS en_US
dc.contributor.department Dept. of Biology en_US
dc.contributor.registration 20081010 en_US


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  • MS THESES [1705]
    Thesis submitted to IISER Pune in partial fulfilment of the requirements for the BS-MS Dual Degree Programme/MSc. Programme/MS-Exit Programme

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