Oxazoles from marine sponge Mycale (Zygomycale) parishii

Mokashe, Satish S.; WATVE, MILIND; Ghanekar, Ruchika Kaul; Lakwal, Vijay R.; Raina, Prerna; Kharate, Dinesh S.; Meesala, Srinu

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Oxazoles from marine sponge Mycale (Zygomycale) parishii

Meesala, Srinu; Lakwal, Vijay R.; Kharate, Dinesh S.; Mokashe, Satish S.; Raina, Prerna; Ghanekar, Ruchika Kaul; WATVE, MILIND

URI: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3567 https://doi.org/10.15373/22778179 Date: 2017-05

Abstract:

Two new oxazole compounds (1&2) along with two known compounds (3&4) were isolated from the methanolic extract of Mycale (Zygomycale) parishii. Their structures were identified on the basis of IR, NMR, and HR-ESI-MS analysis. The oxazole compounds (1&2) showed oad-spectrum activity against bacteria and fungi at 100 -g/disk and exhibited very weak cytotoxic activity against HeLa, SiHa and MDA-MB-231 cell lines

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