4(R/S)-Guanidinylprolyl Collagen Peptides: On-Resin Synthesis, Complexation with Plasmid DNA, and the Role of Peptides in Enhancement of Transfection

dc.contributor.author	NANDA, MANASWINI	en_US
dc.contributor.author	GANESH, KRISHNA N.	en_US
dc.date.accessioned	2019-07-23T11:08:16Z
dc.date.available	2019-07-23T11:08:16Z
dc.date.issued	2012-03	en_US
dc.identifier.citation	The Journal of Organic Chemistry, 77 (8), 4131-4135.	en_US
dc.identifier.issn	0022-3263	en_US
dc.identifier.issn	1520-6904	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3612
dc.identifier.uri	https://doi.org/10.1021/jo300070p	en_US
dc.description.abstract	Chimeric collagen peptides containing cationic 4(R/S)-guanidinylproline are synthesized by in situ amidinylation of 4(R/S)-aminoproline residues. These peptides uniquely enhance the transfection efficiency of GFP-encoded plasmid DNA (pRmHa3-GFP) into cells through efficient DNA condensation resulting from nonspecific electrostatic interactions of cationic guanidino groups and localize in subcytoplasmic organelles.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.subject	Chemistry	en_US
dc.subject	2012	en_US
dc.title	4(R/S)-Guanidinylprolyl Collagen Peptides: On-Resin Synthesis, Complexation with Plasmid DNA, and the Role of Peptides in Enhancement of Transfection	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	The Journal of Organic Chemistry	en_US
dc.publication.originofpublisher	Foreign	en_US