Posttranscriptional chemical functionalization of azide-modified oligoribonucleotides by bioorthogonal click and Staudinger reactions

dc.contributor.author	RAO, HARITA	en_US
dc.contributor.author	Sawant, Anupam A.	en_US
dc.contributor.author	TANPURE, ARUN A.	en_US
dc.contributor.author	SRIVATSAN, SEERGAZHI G.	en_US
dc.date.accessioned	2019-07-23T11:08:48Z
dc.date.available	2019-07-23T11:08:48Z
dc.date.issued	2012-01	en_US
dc.identifier.citation	Chemical Communications, 48(4), 498-500.	en_US
dc.identifier.issn	1359-7345	en_US
dc.identifier.issn	1364-548X	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3621
dc.identifier.uri	https://doi.org/10.1039/C1CC15659D	en_US
dc.description.abstract	Direct incorporation of azide groups into RNA oligonucleotides by in vitrotranscription reactions in the presence of a new azide-modified UTP analogue, and subsequent posttranscriptional chemical labeling of azide-modified oligoribonucleotide transcripts by click and Staudinger reactions are described. This postsynthetic labeling protocol is robust and modular, and offers an alternative access to RNA labeled with biophysical probes.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.subject	Chemistry	en_US
dc.subject	2012	en_US
dc.title	Posttranscriptional chemical functionalization of azide-modified oligoribonucleotides by bioorthogonal click and Staudinger reactions	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Chemical Communications	en_US
dc.publication.originofpublisher	Foreign	en_US