Label-free fluorescence detection of the depurination activity of ribosome inactivating protein toxins

dc.contributor.author	TANPURE, ARUN A.	en_US
dc.contributor.author	Patheja, Pooja	en_US
dc.contributor.author	SRIVATSAN, SEERGAZHI G.	en_US
dc.date.accessioned	2019-07-23T11:08:49Z
dc.date.available	2019-07-23T11:08:49Z
dc.date.issued	2012-01	en_US
dc.identifier.citation	Chemical Communications, 48(4), 501-503.	en_US
dc.identifier.issn	1359-7345	en_US
dc.identifier.issn	1364-548X	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3622
dc.identifier.uri	https://doi.org/10.1039/C1CC16667K	en_US
dc.description.abstract	Development of a simple label-free fluorescence hybridization assay to monitor the depurination activity of toxic ribosome inactivating proteins by using a fluorescent ligand that specifically pseudo base pairs with a cytosine residue opposite an abasic site is described. This method could be potentially implemented in screening platforms for the discovery of small molecules that inhibit the activity of these toxins.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.subject	Chemistry	en_US
dc.subject	2012	en_US
dc.title	Label-free fluorescence detection of the depurination activity of ribosome inactivating protein toxins	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Chemical Communications	en_US
dc.publication.originofpublisher	Foreign	en_US